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Dec 16, 2024

Men's Health

Feeling Tired? It Might Be Low T

Do you often feel tired, even after a good night's sleep? While occasional fatigue is normal, persistent exhaustion could be a sign of a deeper issue. For many men, it may be caused by low testosterone, or low T.

Often associated with muscle growth and strength, testosterone is a hormone that also plays a significant role in energy levels and mood. As men age, testosterone production naturally declines. In fact, approximately 40% of men over 45 experience low T. This gradual decrease can lead to noticeable fatigue, impacting daily life and leaving individuals feeling drained, even with adequate sleep and a healthy lifestyle.

Unfortunately, low T is frequently underdiagnosed, leaving many men unaware of its potential impact on their health. Beyond fatigue, low testosterone can also affect muscle mass, mood, libido, and cognitive function.

Understanding Testosterone

Testosterone, primarily produced in the testes with smaller amounts from the adrenal glands, plays an important role in various bodily functions. It contributes to:

  • Energy regulation
  • Muscle mass development
  • Bone strength
  • Mood stabilization
  • Sperm production
  • Fat distribution
  • Red blood cell production

The brain, specifically the hypothalamus and pituitary gland, regulates testosterone production. The hypothalamus monitors testosterone levels and signals the pituitary gland when more is needed. In response, the pituitary gland instructs the testes to produce additional testosterone, maintaining a balanced level.

Testosterone Throughout Life

During adolescence, testosterone levels surge, driving the development of male characteristics like increased muscle mass, voice deepening, and hair growth. These levels remain elevated in early adulthood, supporting physical vitality and reproductive health. However, after 30, testosterone levels gradually decline.

In addition to its role in reproduction and physical development, testosterone is closely linked to other aspects of health. It supports bone density, helping to reduce the risk of fractures, and impacts the maintenance of muscle strength and endurance. Its influence on red blood cell production helps in oxygen delivery throughout the body, which is important for maintaining energy and physical performance.

Testosterone also affects mental and emotional well-being. It helps regulate mood and has been associated with confidence, motivation, and focus.

Low Testosterone

Low testosterone, or male hypogonadism, occurs when the body produces insufficient levels of testosterone. This condition can result from problems in the testes (primary hypogonadism) or the brain's hypothalamus and pituitary gland (secondary hypogonadism), which regulate hormone production.

One of the most common and often overlooked symptoms of low testosterone is persistent fatigue.

Testosterone plays a key role in energy levels by influencing red blood cell production. When testosterone levels are low, reduced red blood cell production can lead to decreased oxygen availability, contributing to feelings of exhaustion. Additionally, low testosterone can affect muscle health and metabolism, leading to decreased physical endurance and increased fatigue.

The relationship between low testosterone and fatigue is well-supported by research. The Hypogonadism in Males (HIM) study found that about 38.7% of men aged 45 and older have low testosterone levels, with fatigue being a primary complaint among those affected.

Some studies have also noted that men with low testosterone often experience reduced energy and difficulty maintaining physical activity, significantly impacting their quality of life. These findings show how low testosterone can make everyday tasks feel more challenging and contribute to a cycle of inactivity and worsening symptoms.

Fatigue caused by low testosterone often coexists with other symptoms, such as reduced muscle strength, increased body fat, and mood changes, exacerbating the sense of fatigue.

That’s why this impact on physical and mental health makes low testosterone a key factor to consider for men experiencing continuous tiredness.

Symptoms of Low Testosterone

Low testosterone can manifest in a variety of ways, often affecting both physical and mental health. Here are some common symptoms:

Physical Symptoms
  • Persistent Fatigue: A deep, unrelenting tiredness that doesn't improve with rest.
  • Reduced Muscle Mass and Strength: Difficulty building or maintaining muscle mass, leading to weakness.
  • Decreased Bone Density: Increased risk of fractures and osteoporosis.
  • Changes in Body Composition: Increased body fat, particularly around the waist.
  • Reduced Sex Drive (Libido): Decreased interest in sexual activity.
  • Erectile Dysfunction: Difficulty achieving or maintaining an erection.
  • Changes in Sleep Patterns: Difficulty falling asleep, staying asleep, or feeling rested.
  • Smaller Testicle Size: A noticeable decrease in testicle size.
Mental and Emotional Symptoms
  • Mood Changes: Irritability, depression, or anxiety.
  • Lack of Motivation: Decreased interest in activities once enjoyed.
  • Cognitive Impairment: Difficulty concentrating, memory problems, or reduced mental clarity.

If you're experiencing these symptoms, it's important to consult with a healthcare provider to determine the underlying cause. While low testosterone is a common culprit, other factors may be involved. A comprehensive evaluation can help identify the issue and develop an appropriate treatment plan.

Diagnosing Low Testosterone

Diagnosing low testosterone typically involves a combination of medical history review, physical examination, and laboratory tests.

Medical History and Physical Exam

  • Symptom Assessment: Your doctor will ask about specific symptoms you've been experiencing, such as fatigue, reduced sex drive, erectile dysfunction, mood changes, or decreased muscle mass.
  • Physical Examination: A physical exam may include checking for signs of low testosterone, such as reduced testicle size or decreased muscle mass.

Blood Tests

  • Serum Testosterone Test: This is the primary test used to measure the amount of testosterone in your blood. Levels below 300 nanograms per deciliter (ng/dL) are generally considered low, but this can vary.
  • Luteinizing Hormone (LH) Test: LH is a hormone that stimulates testosterone production. Measuring LH levels can help determine the cause of low testosterone. High LH levels may indicate a problem with the testes, while low or normal LH levels may suggest an issue with the brain's hormone-regulating glands.
  • Prolactin Test: Prolactin is a hormone that can interfere with testosterone production. Elevated prolactin levels may indicate an underlying condition, such as a pituitary tumor.

These tests, combined with medical history and lifestyle factors, provide a clearer picture of whether low testosterone is the cause of your symptoms.

When to Seek Medical Attention for Fatigue

If persistent fatigue and other symptoms of low testosterone are affecting your quality of life, it is important to reach out to your doctor for evaluation. Fatigue that does not improve with rest or other common therapy may indicate a deeper issue, such as hormonal imbalance, that requires medical attention. Speaking with your primary care physician or an endocrinologist can provide clarity on the cause of your symptoms and provide a path to improvement.

While low testosterone is not considered an emergency, it is a condition that should not be ignored, particularly if symptoms are persistent or worsening. The sooner you speak with your doctor, the sooner you can begin to manage symptoms.

Treating Low Testosterone

If you are diagnosed with low testosterone treatment options are available. The typical treatment involves replacing testosterone. There are several ways to supplement the hormone: injections, topical gels, and oral capsules.

We currently offer an oral testosterone product called Kyzatrex - $159 for 120 tablets.

References:

  1. Mulligan T, Frick MF, Zuraw QC, Stemhagen A, McWhirter C. Prevalence of hypogonadism in males aged at least 45 years: the HIM study. Int J Clin Pract. 2006;60(7):762-769. doi:10.1111/j.1742-1241.2006.00992.x. PMCID: PMC1569444.

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