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Are you on the right cholesterol drug?


Not all patients are the same. Not all statins are the same.

Atorvastatin vs Pitavastatin in Lowering Cholesterol
Pitavastatin Reduced Potential for Drug Interactions Compared to Other Statins
Statin Pitavastatin Effects on Blood Glucose Compared to Atorvastatin

Key Features of ZYPITAMAG (pitavastatin)

ZYPITAMAG is a third-generation statin that is used alongside changes to diet and exercise to help lower cholesterol in adults.

  • Reduced potential for certain drug interactions compared to simvastatin
  • Provides LDL-C ("bad cholesterol") reduction comparable to simvastatin
  • Lowers LDL-C by up to 45% and increases HDL-C by up to 7%
  • Can be taken with grapefruit juice—unlike some other statins
  • Take anytime—unlike some other statins, which must be taken at night.
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What Our Customers Say

After finding the Marley Drug website and reading about Zypitamag I contacted my physician. After some research he gave me approval to use this medicine. I find Zypitamag effective as I had bloodwork done ...
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T. Thomas
Testimonial Thomas
Zypitamag is a great option. Utilizing Marley Drug to prescribe Zypitamag has greatly improved access to pitavastatin for several of my patients.
Dr. Kimberly Rieniets, D.O
Testimonial Kimberly
I heard about Zypitamag from my cardiologist. It’s working well. My cholesterol is in the normal range now. The Marley Drug staff were very friendly, helpful, and professional.
Laura
Testimonial Laura
The results are back after 2 months on Zypitamag. Wow! My numbers have come way down, and I am so happy with the results!
Richard H.
Testimonial Richard
I just had my 3 month follow up blood work done for my cholesterol after using Zypitamag. The results were outstanding! The best lipid levels I have had in treating cholesterol... I have not had any side ...
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Garrick M
Testimonial Garrick
I have always had trouble with statins. My doctor recommended Marley Drug’s statin, Zypitamag (pitavastatin), and I have been taking that with no side effects and my bad cholesterol has gone down significantly ...
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Jacquie N.
Testimonial Jaquie N
This drug is a miracle for me! I have tried every statin on the market with copious amounts of muscle pain weakness, back pain overall, and aching in every joint. My family has genetic high cholesterol ...
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Nurse from Houston, TX
Testimo Nurse
Zypitamag has made a world of difference in my health. I have not had any side effects of muscle pain. Thank you, Marley Drug for making the process of getting this medication so fast and easy. I never ...
Read More
Anne H.
Testimonical Anne H
Stock photos are used to represent actual testimonials of Marley Drug customers.

What to Consider When Choosing the Right Statin

Choosing the right statin isn’t just about lowering cholesterol—it’s about finding a medication that fits your unique health profile and lifestyle. Here are some key factors to keep in mind:


What Statin Intensity Do I Require?

Statin intensity refers to the degree to which a statin can lower your LDL ("bad") cholesterol levels. Statins are categorized into low, moderate, and high intensity based on their cholesterol-lowering capabilities. The right intensity for you depends on your individual cholesterol goals and medical history.

The Rule of 6

For every doubling of a statin dose, you can expect approximately a 6% additional reduction in LDL cholesterol.

However, increasing the dose often comes with a higher risk of side effects, such as muscle pain or liver enzyme elevations.

This means that while doubling a statin dose can offer a slight improvement in cholesterol reduction, the trade-off may not always be worth it.

How ZYPITAMAG Compares to Atorvastatin
  • ZYPITAMAG 2mg offers similar LDL-lowering benefits to Atorvastatin 10mg.
  • ZYPITAMAG 4mg is comparable to Atorvastatin 20mg in terms of reducing LDL cholesterol.

If you're not meeting your LDL-C goals with a statin alone, instead of simply increasing the dose, you might benefit from combination therapy. Adding a medication like ezetimibe, which blocks cholesterol absorption in the intestine, can provide significant additional LDL reduction without increasing statin side effects.


Statins and their Effect on Blood Sugar

Statins can increase blood sugar levels. Data suggests that statins like ZYPITAMAG (pitavastatin), may have less of an effect on this compared to other statins. Click the link below to download a free resource that dives into this topic in detail.

Free Educational Resource: Statins Effects on Blood Sugar Guide.


If You're Taking Multiple Medications

70-80% of medications, including atorvastatin, are metabolized by the same enzyme family called the cytochrome 450 (CYP450) family of enzymes.

Newer statins, like ZYPITAMAG, bypass these enzyme pathways and have reduced potential for drug-drug and drug-food interactions.


Side Effects and Tolerability

In general, higher doses of statins are associated with a greater likelihood of side effects. If you experience side effects while taking a statin, it’s important to speak with your healthcare provider. They may recommend lowering your dose or switching to a different statin to see how your body responds.

Muscle Pain: The #1 Reason People Stop Taking Statins

Muscle pain is the most commonly reported reason for discontinuing statin use.

However, there is hope, as a recent study found that the majority of those who experienced statin side effects, with proper consultation from their healthcare provider, can switch doses or statins to find a statin that works for them.

This finding underscores the importance of discussing any discomfort with your doctor to determine the true cause and explore alternative options.

If you’re facing these challenges, switching to a moderate intensity statin like ZYPITAMAG (pitavastatin) may be a good option.

Why ZYPITAMAG May Be the Right Choice for You

ZYPITAMAG, a next-generation statin, is a proven alternative for patients looking for effective cholesterol management. Here’s why it stands out:

  • Proven Effectiveness: ZYPITAMAG has been shown to significantly lower LDL cholesterol levels by up to 45%. If additional cholesterol lowering is needed ezetimibe can be added on as additional therapy.
  • Well-Tolerated: Designed for patients sensitive to traditional statins, ZYPITAMAG has a reduced potential for drug-drug and drug-food interactions compared to most statins.
  • Accessible and Affordable: Through Marley Drug's Direct-to-Patient model - the most you will pay for ZYPITAMAG is $34.50/month. And if its covered by your insurance, it may be as low as $0/month.

How to Get Started with ZYPITAMAG

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Consult Your Doctor

Discuss your symptoms, concerns, and goals to see if ZYPITAMAG is the right fit for you.

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Send Your Prescription to Marley Drug

If ZYPITAMAG is right for you, be sure to access ZYPITAMAG through Marley Drug’s Direct-to-Patient program, ensuring affordability and convenience.

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We will ship it to your home

We offer free shipping to all 50 states. Our average delivery time is 2 days.

Pharmacists Padding Top And Bottom

Have questions about statins?
Talk with a pharmacist today.

Call us for a free pharmacy consult.

800-810-7790

Common Questions About Statins

How do I know if Zypitamag is right for me?

If you’ve experienced side effects with Atorvastatin or are looking for a more personalized statin option, talk to your healthcare provider. They can help determine if Zypitamag fits your health goals and medical history.

Are there lifestyle changes I can combine with Zypitamag for better results?

Absolutely! Pairing Zypitamag with a healthy diet, regular exercise, and weight management can enhance cholesterol-lowering results and improve overall heart health.

How can I get Zypitamag?

Zypitamag is available through Marley Drug, offering an affordable, direct-to-patient program. This ensures that you receive your medication conveniently and at a competitive price.

Can I switch directly from Atorvastatin to Zypitamag?

Switching statins should always be done under the guidance of your healthcare provider. They can assess your specific needs and recommend the appropriate dosage to ensure a smooth transition.

Is Zypitamag safe for people with diabetes?

Zypitamag is a good choice for patients with diabetes. It has a favorable metabolic profile and is less likely to affect blood sugar levels compared to some other statins. However, like all statins, there is risk that it can raise blood glucose levels.

How does Zypitamag compare to Atorvastatin?

Zypitamag 2mg and 4mg offers similar cholesterol-lowering benefits to Atorvastatin 10 and 20mg. It’s may be a better option for certain patients, such as those taking multiple medications, thanks to its reduced potential for interactions.

You can read an article which directly compares atorvastatin with pitavastatin here.

What is Zypitamag, and how does it work?

Zypitamag is a third-generation statin that effectively lowers LDL cholesterol by reducing cholesterol production in the liver. It’s particularly known for being well-tolerated, with a lower risk of muscle-related side effects and fewer drug interactions compared to some other statins.

Why might I need an alternative to Atorvastatin (Lipitor)?

Many patients tolerate Atorvastatin well, but some may experience side effects like muscle pain, fatigue, or digestive issues. Others may have concerns about drug interactions or seek a statin better suited to their unique health profile. Exploring alternatives like Zypitamag (pitavastatin) can help address these concerns.