ORDER TORSEMIDE

<h1><strong>Get Torsemide</strong> (generic Demadex<sup>®</sup>) <strong>for $70/year</strong></h1>
<br>

<ul>
<li>Wholesale pricing&mdash;so you pay less</li>
<li>Fill in longer supply&mdash;up to 12 months at a time</li>
<li>One price regardless of dose&mdash;no price fluctuations</li>
</ul>

<p>Fewer pharmacy visits. Fill in 30-, 90-, 180-, or 360-day supply at a time.</p>

Low-Cost Generic Torsemide

<h2><strong>What is Torsemide</strong>?</h2><p>Torsemide is prescription medication taken by mouth. It is used to treat high blood pressure as well as edema (fluid retention) that is caused by heart failure or kidney disease. Torsemide is part of a class of medications called <a href="https://www.marleydrug.com/blog/diuretics-for-blood-pressure" rel="noopener noreferrer" target="_blank">loop diuretics</a>.</p><h4><strong>New Formulation of Torsemide Available - SOAANZ </strong></h4><p>SOAANZ is a novel formulation of torsemide that releases drug slowly and induces sustained and prolonged diuresis.</p><p> <strong>SOAANZ may benefit patients who experience worsening bladder problems with the use of a generic loop diuretic. </strong></p><p style="background-color:#FFFFFF; border: 2px dotted #8DA3A8; text-align:center;">Learn more about <a href="https://www.marleydrug.com/soaanz" rel="noopener noreferrer" target="_blank">SOAANZ (torsemide) and how to access it through Marley Drug</a>.</p>

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<p class="ql-align-center">Through our online portal we will ask you to provide us your medical history and prescription details. Questions? Call&nbsp;<a href="tel:800-810-7790" rel="noopener noreferrer">800-810-7790</a>.</p>

Provide us your prescription details

<p class="ql-align-center">Our pharmacy team will verify your prescription details and even contact your healthcare provider on your behalf if you want.</p>

We'll verify your prescription

<p class="ql-align-center">All medications are shipped by USPS First Class mail and will arrive in 2-3 business days.</p>

Your medication will be shipped to your home

How to Order Torsemide

<h2><strong>Do you have worsening problems while taking a loop diuretic like torsemide?</strong></h2><p>In 2021 a new formulation of torsemide was approved by the FDA called SOAANZ.<br><br> SOAANZ <strong>releases drug more slowly</strong> than torsemide and therefore there isn't such a high spike of drug in your blood after taking it. This key different may help improve bladder issues those experience while taking torsemide, but also allows the medication to work for a longer period of time. </p><p style="background-color:#FFFFFF; border: 2px dotted #8DA3A8; text-align:center;">Learn more about <a href="https://www.marleydrug.com/soaanz" rel="noopener noreferrer" target="_blank">SOAANZ (torsemide) and how to access it through Marley Drug</a>.</p>

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<h2>Have medication questions?<br>Talk with a pharmacist today.</h4>
<p>Call us for a free pharmacy consult.<br><br>
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The Wholesale Price List made my prescription easy to afford,  I was about to cancel my prescription because my monthly cost with insurance was almost $150!  Now I can get a 6-month supply for only $37, which is much less money than a one month supply using my insurance. Thanks Dee for calling and letting me know my options!

My doctor had tried me on other cholesterol medications, but I could not tolerate them. Marley Drug was a “lifesaver” in getting me my Zypitamag. A monthly prescription of pitavastatin was about $240 at all of my local pharmacies. This is cost prohibitive and ridiculous!   Thanks to Marley, my cholesterol is now under control. And the staff was prompt and helpful!  Thanks Marley Drugs!

I have always had trouble with statins. My doctor recommended Marley Drug’s statin, Zypitamag (pitavastatin), and I have been taking that with no side effects and my bad cholesterol has gone down significantly. It is a relief to find a statin drug that gives me no side effects.

Zypitamag has made a world of difference in my health. I have not had any side effects of muscle pain. Thank you, Marley Drug for making the process of getting this medication so fast and easy. I never have any problems or delays in your service. You guys are great!

As soon as my doctor submitted the prescription, I was contacted by Terri, who explained the process and set up delivery to my home. It could not have been easier!

What Our Customers Have to Say

Common Questions on Torsemide

<p><em>Blood pressure measures the force of your blood in your blood vessels. If the pressure is too high it can cause damage to your arteries and cause <a href="https://www.marleydrug.com/blog/why-is-it-important-to-manage-your-blood-pressure" target="_balnk">numerous health complications</a>. Therefore, it is important to keep track and manage your blood pressure.</em></p>

<h2>How to Read Your Blood Pressure</h2>

<p style="margin-bottom:10px;">Blood pressure readings consist of two numbers:</p>
<ul>

<li style="margin-bottom:10px;"><span style="border-bottom:.125em #fee203 solid; font-weight:600;">Systolic blood pressure:</span> The first number in the reading indicates how much pressure is in the blood when the heart contracts (during a heartbeat).</li>

<li style="margin-bottom:10px;"><span style="border-bottom:.125em #fee203 solid; font-weight:600;">Diastolic blood pressure:</span> This is the second number in a blood pressure reading that indicates the pressure of your blood when the heart relaxes (between heartbeats).</li>

</ul>


<p>These two numbers represent the average pressure of your blood and are compared against the healthy numbers to see if the pressure is elevated.</p>

<p>If you aren’t sure which number is which, an easy trick to remember is that the diastolic is always lower than the systolic number.</p>


<h2>What is Normal Blood Pressure? </h2>

<p>Depending on how much higher your blood pressure is to 120/80 it will indicate the severity of <a href="https://www.marleydrug.com/high-blood-pressure">high blood pressure</a>.</p>

<img src="https://marley-storage.imgix.net/443c888d-55cc-4157-92b2-f782ef387dac/blood-pressure-categories.png" alt="Blood Pressure Readings" width="800" height="auto" style="display:block; max-width:100%;">

<br>


<ul>
         <li style="margin-bottom:10px;"><span style="border-bottom:.25em solid #7fb523;  font-weight:600;">Normal</span>: These are the levels that indicate a healthy blood pressure.</li>
         <li style="margin-bottom:10px;"><span style="border-bottom:.25em solid #ffeb51; font-weight:600;">Elevated</span>: These levels indicate that you are more likely to develop high blood pressure unless changes are made to your lifestyle to prevent this.</li>
         <li style="margin-bottom:10px;"><span style="border-bottom:.25em solid #f78c21; font-weight:600;">Hypertension Stage 1</span>: At this stage, you are at a higher risk of developing conditions such as heart disease. Your doctor may choose to prescribe blood pressure medications to help manage your blood pressure or recommend lifestyle changes.</li>
        <li style="margin-bottom:10px;"><span style="border-bottom:.25em solid #f1491c; font-weight:600;">Hypertension Stage 2</span>: This stage presents high risk of chronic health problems and lasting damage to your arteries. Your doctor may recommend a combination of medication and lifestyle changes to combat HBP.</li>
        <li style="margin-bottom:10px;"><span style="border-bottom:.25em solid #c1280e; font-weight:600;">Hypertensive Crisis</span>: This stage requires immediate medical intervention, as leaving it untreated could be fatal.</li>
</ul>

<h2>Managing Your Blood Pressure</h2>

<h4><strong>Lifestyle Changes</strong></h4>

<p style="margin-bottom:10px;">Here are a number of lifestyle changes you can make to help lower your blood pressure:</p>

<ul>
      <li style="margin-bottom:10px;">Reducing alcohol consumption</li>
      <li style="margin-bottom:10px;">Regular physical activity</li>
      <li style="margin-bottom:10px;">Healthy diet</li>
      <li style="margin-bottom:10px;">Quit  tobacco consumption</li>
      <li style="margin-bottom:10px;"><a href="https://www.marleydrug.com/blog/how-stress-affects-your-body">Managing stress</a></li>
</ul>

<h4><strong>Medications</strong></h4>

<p>If you are struggling to manage your blood pressure or are at risk of health complications, your doctor may <a href="https://www.marleydrug.com/blog/how-to-lower-high-blood-pressure-hypertension#bp medications" target="_blank">prescribe you medication to help you manage it</a>. There are five different types of medication:</p>

<ul>
      <li style="margin-bottom:10px;"><a href="https://www.marleydrug.com/blog/diuretics-for-blood-pressure">Diuretics</a>
</li>
      <li style="margin-bottom"10px;"><a href="https://www.marleydrug.com/blog/what-are-beta-blockers">Beta-blockers</a></li>
      <li style="margin-bottom:10px;"><a href="https://www.marleydrug.com/blog/ace-inhibitors" target="_blank">ACE inhibitors</a></li>
      <li style="margin-bottom:10px;">ARBs</li>
      <li style="margin-bottom:10px;"><a href="https://www.marleydrug.com/blog/calcium-channel-blockers-and-high-blood-pressure" target="_blank">Calcium channel blockers</a></li>
</ul>

<p>Marley Drug offers medications from all five categories for an affordable wholesale price. Check our <a href="https://www.marleydrug.com/wholesale-price-list-medications" target="_blank">Wholesale Price List</a> for your medications. If you have any questions about medications or Marley Drug, call us at <a href="tel:800-810-7790">800-810-7790</a> and speak to our pharmacy team today.</p>

Blood pressure measures the force of your blood in your blood vessels. If the pressure is too high it can cause damage to your arteries and cause numerous health complications. Therefore, it is important to keep track and manage your blood pressure.

What do systolic and diastolic numbers mean? You can manage your blood pressure with lifestyle changes and/or medications such as beta blockers, diuretics, and ACE inhibitors.

Understanding Blood Pressure Readings

Blood Pressure

<p style="background-color:#F0F3F5; padding:20px; border-left:5px solid #fee203; margin: 20px 0 30px 0; font-size:1.2em">You’ve probably seen countless articles about how to manage your <a href="https://www.marleydrug.com/blog/how-to-lower-high-blood-pressure-hypertension" target="_blank">blood pressure</a> and products advertised as something that “helps to lower your blood pressure”, but what exactly are the risks of having high blood pressure? Alternatively, is there such thing as “too low?”</p>

<h2>Effects of <a href="https://www.marleydrug.com/high-blood-pressure">High Blood Pressure</a></h2>

<p style="margin-bottom:10px;">If blood pressure is elevated for too long it puts strain on the body and can lead to several serious and permanent health complications and conditions such as:</p>

<ul>
     <li style="margin-bottom:7px;">Heart attacks/heart failure</li>
     <li style="margin-bottom:7px;"><a href="https://www.marleydrug.com/stable-angina">Angina (chest pain)</a></li>
     <li style="margin-bottom:7px;">Aneurisms</li>
     <li style="margin-bottom:7px;"><a href="https://www.marleydrug.com/blog/what-is-stroke">Strokes</a></li>
     <li style="margin-bottom:7px;">Loss of vision</li>
     <li style="margin-bottom:7px;">Kidney disease/failure</li>
     <li style="margin-bottom:7px;">Pregnancy complications</li>
     <li style="margin-bottom:7px;">Memory impairment/dementia</li>
     <li style="margin-bottom:7px;">Sexual dysfunction</li>
</ul>


<h2>Effects of Low Blood Pressure</h2>

<p style="margin-bottom:10px;">Although it is not as serious since it does not place strain on your blood vessels and cause lasting damage like high blood pressure does, having low blood pressure can also lead to unpleasant symptoms including:</p>

<ul>
     <li style="margin-bottom:7px;">Fatigue and dizziness</li>
     <li style="margin-bottom:7px;">Nausea</li>
     <li style="margin-bottom:7px;">Trouble concentrating</li>
     <li style="margin-bottom:7px;">Blurred vision</li>
     <li style="margin-bottom:7px;">Fainting</li>
</ul>

<h2>How to Manage Your Blood Pressure</h2>

<p>Overall, it is important to be aware of what can affect your blood pressure and make sure it stays within a normal range.</p>

<h4><strong>Regulating Blood Pressure at Home</strong></h4>

<img src="https://marley-storage.imgix.net/c44a0221-46e4-4593-9474-6c7280d8ca3e/healthy-lifestyle.jpg" alt="Lifestyle changes for managing blood pressure" width="900" height="auto" style="display:block; max-width:100%;">
<br>
<p>There are many lifestyle changes you can make to help regulate your blood pressure today.</p>

<p><span style="border-bottom:.125em #fee203 solid; font-weight:600;">Proper Nutrition:</span> unhealthy eating and overeating can lead to high blood pressure while malnutrition and undereating can cause low blood pressure. It is important to make sure you are getting enough energy from nutrient-rich foods and avoid processed sugars which can put further strain on your arteries. Potassium and sodium both greatly contribute to lowering and heightening your blood pressure. It is important that you are consuming enough potassium and limiting your sodium intake to avoid hypertension.</p>

<p><span style="border-bottom:.125em #fee203 solid; font-weight:600;">Proper Hydration:</span> Dehydration can lead to low blood pressure among other complications. It is important that you are drinking enough water throughout the day.</p>

<p><span style="border-bottom:.125em #fee203 solid; font-weight:600;">Tobacco Consumption:</span> One effect of tobacco use is an instant increase in your blood pressure. Over time this can cause damage to your arteries and increase your risk of heart disease.</p>

<p><span style="border-bottom:.125em #fee203 solid; font-weight:600;">Alcohol Consumption:</span> Long term heavy drinking can damage your heart and put you at risk for many serious health complications. If you drink, be sure to do so in moderation and do not exceed the recommended limit of one drink per day for women and two drinks per day for men.</p>

<p><span style="border-bottom:.125em #fee203 solid; font-weight:600;">Physical Activity:</span> Being overweight or not being physically active can put you at greater risk of high blood pressure. To strengthen your heart muscle, regular physical activity is key. Being at a healthy weight will also reduce any added strain to the heart.</p>

<p><span style="border-bottom:.125em #fee203 solid; font-weight:600;">Stress:</span> <a href="https://www.marleydrug.com/blog/how-stress-affects-your-body">Stress</a> can have an impact on your overall health. Related to your blood pressure, lowering your stress level is important for maintaining a healthy blood pressure level. Taking time out of your busy schedule to go on a short walk helps decrease stress and has the added benefit of keeping you regularly active.</p>


<h4><strong>Medicine for Blood Pressure</strong></h4>

<p>If you have made the necessary lifestyle adjustments and continue to struggle to manage your blood pressure, your doctor may prescribe you with additional medications that will make regulating your blood pressure easier.</p>

<p style="margin-bottom:10px;">There are five different types of medications that can be prescribed to treat high blood pressure:</p>

<ul>
      <li style="margin-bottom:7px;"><a href="https://www.marleydrug.com/blog/ace-inhibitors" target="_blank">Angiotensin-Converting Enzyme (ACE) Inhibitors</a></li>
      <li style="margin-bottom:7px;"><a href="https://www.marleydrug.com/blog/what-is-a-angiotensin-receptor-blocker" target="_blank">Angiotensin II Receptor Blockers (ARBs)</a></li>
      <li style="margin-bottom:7px;"><a href="https://www.marleydrug.com/blog/diuretics-for-blood-pressure" target="_blank">Diuretics</a></li>
      <li style="margin-bottom:7px;"><a href="https://www.marleydrug.com/blog/calcium-channel-blockers-and-high-blood-pressure" target="_blank">Calcium Channel Blockers (CCB)</a></li>
      <li style="margin-bottom:7px;"><a href="https://www.marleydrug.com/blog/what-are-beta-blockers" target="_blank">Beta-Blockers</a></li>
</ul>

<p>Marley Drug offers medications from each of these classes at affordable prices available with no insurance needed.  Check to see if we offer your medications on our <a href="https://www.marleydrug.com/wholesale-price-list-medications" target="_blank">Wholesale Price List</a> or call us at <a href="tel:800-810-7790">800-810-7790</a> and speak to our pharmacy team with any questions you may have about medications or our services.</p>

You’ve probably seen countless articles about how to manage your blood pressure and products advertised as something that “helps to lower your blood pressure”, but what exactly are the risks of having high blood pressure? Alternatively, is there such thing as “too low?”

It is important to be aware of what can affect your blood pressure and make sure it stays within a normal range. Learn about how you can manage your blood pressure.

Why is it important to manage your blood pressure

Why is it important to manage your blood pressure?

<div style="font-size:16px; line-height:1.4; font-weight:600; margin-top:30px; margin-bottom: 40px; padding-top: 30px; border-top: 1px dotted #8a8a8a; border-bottom: 1px dotted #8a8a8a;">
<ul>
<li style="margin-bottom:10px;  line-height:1.4;">Diuretics (water pills) help the kidneys to excrete more sodium into urine. They are used to treat <a href="https://www.marleydrug.com/blog/how-to-lower-high-blood-pressure-hypertension">high blood pressure</a>, <a href="https://www.marleydrug.com/heart-failure">heart failure</a>, edema, liver failure, kidney disorders and glaucoma. </li>
<li style="margin-bottom:10px; line-height:1.4;">There are three major types of diuretics: loop, thiazide and potassium sparing diuretics.</li>
<li style="margin-bottom:10px; line-height:1.4;">The order of potency: loop > thiazide > potassium sparing diuretics.
           <ul>
                  <li style="line-height:1.4; margin-bottom:5px; font-weight:400;">Loop diuretics: <a href="https://www.marleydrug.com/blog/furosemide-lasix" target="_blank">Furosemide</a>, <a href="https://www.marleydrug.com/blog/bumetanide-bumex" target="_blank">Bumetanide</a>, <a href="https://www.marleydrug.com/blog/torsemide" target="_blank">Torsemide</a>, <a href="https://www.marleydrug.com/blog/ethacrynic-acid-edecrin" target="_blank">Ethacrynic Acid</a> </li>
                  <li style="line-height:1.4; margin-bottom:5px; font-weight:400;">Thiazide diuretics: Chlorothiazide, Chlorthalidone, <a href="https://www.marleydrug.com/blog/hydrochlorothiazide" target="_blank">Hydrochlorothiazide, <a href="https://www.marleydrug.com/blog/indapamide-lozol" target="_blank">Indapamide</a>, Metolazone </li>
                  <li style="line-height:1.4; margin-bottom:5px; font-weight:400;">Potassium sparing diuretics: <a href="https://www.marleydrug.com/blog/amiloride-midamor" target="_blank">Amiloride</a>,  <a href="https://www.marleydrug.com/blog/eplerenone-inspra" target="_blank">Eplerenone</a>, <a href="https://www.marleydrug.com/blog/spironolactone-aldactone" target="_blank">Spironolactone</a>, <a href="https://www.marleydrug.com/blog/triamterene-dyrenium" target="_blank">Triamterene</a></li>
          </ul>
</li>
</ul>
</div>

<p style="background-color:#F0F3F5; padding:20px; border-left:5px solid #fee203; margin: 20px 0 30px 0;"><em>Diuretics, known as water pills, are among the most frequently prescribed medications. These drugs are prescribed by doctors to treat a variety of ailments, including congestive heart failure and high blood pressure.</em></p>

<h2>What are Diuretics?</h2>

<p>Diuretics, often referred to as “water pills” or “fluid pills,” are a drug class of medications that help your kidneys excrete more sodium in your urine. They work by reducing sodium reabsorption at several locations in your kidneys which increases sodium and water losses through urination. Correspondingly, the most common side effect of taking water pills is <strong>frequent urination</strong>.</p>

<P>The amount of fluid passing through your veins and arteries is reduced as a result of sodium's ability to eliminate water from your blood, causing your blood pressure to decrease as well as
relieving symptoms such as ankle swelling.</p>

<p>There are various types of diuretic drug classes, including loop diuretics, potassium-sparing diuretics, and thiazide diuretics. Each drug class operates differently and affects different kidney cell regions called nephrons.</p>

<h2>What Are Diuretics Used For?</h2>

<p>Diuretics are prescribed to treat medical conditions such as heart failure, kidney failure, and liver cirrhosis (late stage of scarring (fibrosis) of the liver) that manifest as fluid retention (also known as edema). They are also effective at lowering blood pressure, such as thiazides and loop diuretics, and some diuretics are used as a first-line treatment for high blood pressure (hypertension).</p>

<p>Your doctor may add additional blood pressure medications to your treatment regimen if diuretics are unable to sufficiently decrease your blood pressure.</p>

<p style="margin-bottom:10px;"></p>

<ul>
       <li style="margin-bottom:10px; line-height:1.4;"><span style="border-bottom:.125em #fee203 solid; font-weight:600;">High blood pressure</span>
       &mdash;Diuretics lower blood pressure, which reduces your chance of a heart attack or stroke.
</li>

       <li style="margin-bottom:10px; line-height:1.4;"><span style="border-bottom:.125em #fee203 solid; font-weight:600;">Heart failure</span>
       &mdash;Loop diuretics are commonly used to ease swelling and congestion in your lungs.
</li>

       <li style="margin-bottom:10px; line-height:1.4;"><span style="border-bottom:.125em #fee203 solid; font-weight:600;">Tissue swelling (edema)</span>
       &mdash;Diuretics reduce edema, which typically affects your legs.
</li>

       <li style="margin-bottom:10px; line-height:1.4;"><span style="border-bottom:.125em #fee203 solid; font-weight:600;">Liver failure</span>
       &mdash;Diuretics ease the fluid buildup in individuals with cirrhosis.
</li>

       <li style="margin-bottom:10px; line-height:1.4;"><span style="border-bottom:.125em #fee203 solid; font-weight:600;">Certain kidney disorders</span> (i.e.kidney stones)</li>

       <li style="margin-bottom:10px; line-height:1.4;"><span style="border-bottom:.125em #fee203 solid; font-weight:600;">Glaucoma</span>
       &mdash;Diuretics have been shown to reduce the pressure in your eye(s).
</li>
</ul>

<img src="https://marley-storage.imgix.net/3e99dd63-ce92-49bd-8706-496946aecc75/nephron-3.png" width="900" height="auto" style="display:block; max-width:100%;">

<h2>What Are The Different Types of Diuretics?</h2>

<p style="margin-bottom:10px;">As mentioned, there are 3 types of diuretics: thiazide, potassium sparing and loop diuretics.</p>

<h4 style="margin-bottom:10px; margin-top:15px; color:#5ba2b6; font-weight:600;">Thiazide Diuretics</h4>

<p>Thiazide diuretics inhibit sodium absorption in the distal convoluted tubules, causing increased excretion of sodium, chloride, water, and potassium into urine. These medications are primarily used in hypertension treatment. Thiazide diuretics are inexpensive, effective, and have mild side effects in most individuals.</p>


<div style="background-color:#F0F3F5; padding:20px 20px 5px 20px; margin: 20px 0 30px 0;">

<p style="margin-bottom:10px;">Common thiazide diuretics:</p>

<ul>
        <li style="margin-bottom:7px; line-height:1.4;">Chlorothiazide (band: Diuril) <em>500&ndash;2,000 mg daily in 1&ndash;2 divided doses</em></li>
        <li style="margin-bottom:7px; line-height:1.4;"><strong>Chlorthalidone</strong> <em>12.5&ndash;25 mg daily</em></li>
        <li style="margin-bottom:7px; line-height:1.4;"><strong>Hydrochlorothiazide (HCTZ)</strong> (brand: <strong>Microzide</strong>) <em>12.5&ndash;5- mg daily</em></li>        
       <li style="margin-bottom:7px; line-height:1.4;">Indapamide <em>1.25&ndash;5 mg daily</em></li>
        <li style="margin-bottom:7px; line-height:1.4;">Metolazone <em>2.5&ndash;5 mg daily</em></li>
</ul>

</div>

<p>Thiazide diuretics should be taken in the morning to avoid nocturia (urinating frequently at night).</p>

<h5 style="margin-bottom:15px; font-weight:600;">Common side effects:</h5>

<ul>
        <li style="line-height:1.4; margin-bottom:10px;"><strong>Hypokalemia</strong> (potassium deficiency in your blood; serum potassium level of less than 3.5 mEq/L)</li>
        <li style="line-height:1.4; margin-bottom:10px;"><strong>Hypomagnesemia</strong> (magnesium deficiency in your blood; serum magnesium level of less than 1.4 mEq/L)</li>
        <li style="line-height:1.4; margin-bottom:7px;"><strong>Hyponatremia</strong> (lower than normal sodium level in your blood; serum sodium level of less than 135 mEq/L)</li>
        <li style="line-height:1.4; margin-bottom:10px;"><strong>Hypercalcemia</strong> (above normal calcium level in your blood serum level over 12 mg/dL)</li>
        <li style="line-height:1.4; margin-bottom:10px;"><strong>Hyperuricemia</strong> (above normal uric acid in your blood; serum level over 7 mg/dL)</li>
        <li style="line-height:1.4; margin-bottom:10px;"><strong>Elevated lipids</strong>, such as increased LDL and TG (triglycerides)</li>
        <li style="line-height:1.4; margin-bottom:10px;"><strong>Hyperglycemia</strong> (above normal glucose; greater than 125 mg/dL while fasting)</li>
        <li style="line-height:1.4; margin-bottom:10px;">Dizziness</li>
        <li style="line-height:1.4; margin-bottom:10px;">Photosensitivity</li>
        <li style="line-height:1.4; margin-bottom:10px;">Rash</li>

</ul>

<h5 style="margin-bottom:10px; font-weight:600;">Drug interactions with thiazide diuretics:</h5>

<p><span style="border-bottom:.125em #fee203 solid; font-weight:600;">Avoid drugs that can cause sodium and water retention</span>, such as Nonsteroidal anti-inflammatory drugs (NSAIDs), as they can decrease the effectiveness of antihypertensive medications.</p>

<p>All antihypertensive drugs (medications used to treat high blood pressure) can enhance the blood pressure lowering effects of other drugs; carefully monitor your blood pressure when adding on treatment.</p>

<h4 style="margin-bottom:10px; color:#5ba2b6; font-weight:600;">2.	Potassium-Sparing Diuretics</h4>

<p>Potassium-sparing diuretics, also called aldosterone receptor antagonists (ARA), are medications that increase diuresis (urination) without the loss of potassium.</p>

<p>This drug class functions as antagonists at the aldosterone receptor or as weak diuretics by interfering with the sodium-potassium exchange in the distal convoluted tubule of your kidneys</p>

<p>When potassium-sparing diuretics are used to counteract the impact of aldosterone, more sodium and water can pass into the collecting ducts of your kidneys, increasing diuresis.</p>

<p>These medications <strong>do not produce hypokalemia</strong> (low potassium levels) because they do not cause the secretion of potassium during diuresis. When combined with medications that also retain potassium, such as ACE inhibitors, they <strong>can cause hyperkalemia</strong> (high potassium levels).</p>


<div style="background-color:#F0F3F5; padding:20px 20px 5px 20px; margin: 20px 0 30px 0;">

<p style="margin-bottom:10px;">Common potassium-sparing diuretics:</p>

<ul style="line-height:1.4;">

<li><strong>Amiloride</strong> <em>5&ndash;10 mg daily</em><br>
      <ul>
            <li>Has minimal blood pressure lowering effects and is most commonly used in combination with HCTZ (i.e. Maxzide, Dyazide) to counteract the mild potassium losses sen with thiazide diuretics.</li>
       </ul>    
</li>

<li><strong>Eplerenone</strong> (brand: Inspra) <em>50 mg daily or BID (twice a day)</em><br>
       <ul>
               <li style="margin-bottom:15px;">A preferred add-on drug in individuals with resistant hypertension (uncontrolled blood pressure despite maximum tolerated doses of calcium channel blockers (CCB) + thiazide diuretics + ACE inhibitors or angiotensin II receptor blockers (ARBs)) and is commonly used in heart failure.</li>
               <li style="margin-bottom:15px;">Eplerenone is a selective aldosterone receptor antagonist that does not exhibit endocrine side effects</li>
               <li style="margin-bottom:15px;">Common side effects include hypertriglyceridemia (excess triglycerides in your blood).</li>
         </ul>
</li>

<li><strong>Spironolactone</strong> (Aldactone, CaroSpir oral solution) <em>25&ndash;100 mg daily in 1-2 divided doses</em>
            <ul>
                    <li style="margin-bottom:15px;">A preferred add-on drug in individuals with resistant hypertension (uncontrolled
blood pressure despite maximum tolerated doses of calcium channel blockers (CCB)
+ thiazide diuretics + ACE inhibitors or angiotensin II receptor blockers (ARBs)) and is commonly used in heart failure.</li>
                    <li style="margin-bottom:15px;">Spironolactone is a non-selective aldosterone receptor antagonist that also blocks aldosterone.</li>
                    <li style="margin-bottom:15px;">Common side effects include gynecomastia (a condition that causes a male’s breasts to swell and become larger than normal), breast tenderness, impotence (inability to have an erection during sexual intercourse), irregular menses (periods), and amenorrhea (the absence of periods).</li>
             </ul>           
  </li>

<li><strong>Triamterene</strong> (Dyrenium) <em>100&ndash;300 mg daily in 1&ndash;2 divided doses</em>
       <ul>
               <li>Has minimal blood pressure lowering effects and is most commonly used in combination with HCTZ (i.e. Maxzide, Dyazide) to counteract the mild potassium losses sen with thiazide diuretics.</li>
       </ul>
</li>

<li><strong>Triamterene + HCTZ </strong>(brand: Maxzide, Maxzide-25, Dyazide) <em>37.5 mg/25 mg daily or BID, or 75 mg/50 mg daily</em></li>
</ul>

</div>

<h5 style="margin-bottom:10px; font-weight:600;">Common side effects of potassium-sparing  diuretics:</h5>

<ul>
        <li style="margin-bottom:5px;">Dehydration</li>
        <li style="margin-bottom:5px;">Hyponatremia (low sodium levels in your blood)</li>
        <li style="margin-bottom:5px;">Dizziness</li>
</ul>

<p>Black Box Warning (the highest safety-related warning that medications can have assigned by the FDA): Amiloride and triamterene may cause hyperkalemia (potassium serum level greater than 5.5 mEq/L). This is more likely in individuals with diabetes, renal impairment, or elderly people.</p>

<h4 style="margin-bottom:10px; color:#5ba2b6; font-weight:600;"><a name="loopdiurectics">3.	Loop Diuretics</a></h4>

<p>Loop diuretics are often used to decrease fluid volume to make it easier for your heart to pump. This drug class blocks sodium and chloride reabsorption in the ascending limb of the loop of Henle, interfering with the chloride-binding co-transport system. They increase the excretion of sodium, potassium, chloride, magnesium, calcium, and water. Loop diuretics are also used to reduce congestive symptoms (reduce preload) and restore euvolemia (or “dry” weight).</p>

<p>If the response to loop diuretics is poor, a combination with thiazide-type diuretics, such as metolazone, can be useful.</p>

<p>These medications can be used for blood pressure reduction in individuals with renal impairment when other options are not adequate.</p>


<div style="background-color:#F0F3F5; padding:20px 20px 5px 20px; margin: 20px 0 30px 0;">

<p style="margin-bottom:10px; font-weight:400;">Common loop diuretics:</p>

<ul style="line-height:1.4;">
       <li style="margin-bottom:5px;"><strong>Furosemide </strong>(Lasix) <em>20&ndash;40 mg daily or BID</em></li>
       <li style="margin-bottom:5px;"><strong>Bumetanide</strong> (Bumex) <em>0.5&ndash;1 mg daily or BID</em></li>
       <li style="margin-bottom:5px;"><strong>Torsemide</strong> (Demadex) <em>10&ndash;20 mg daily</em></li>
       <li style="margin-bottom:5px;"><strong>Ethacrynic Acid</strong> (Edecrin) <em>50&ndash;200 mg daily or divided</em></li>
</ul>
</div>

<p>Loop diuretics should be taken in the morning to avoid nocturia (urinating frequently at night). </p>

<h5 style="margin-bottom:10px; font-weight:600;">Common side effects of loop diuretics:</h5>

<ul style="line-height:1.4;">
       <li style="margin-bottom:10px;">Hypokalemia (lower than normal potassium in your blood; serum potassium level lower than 3.5 mEq/L)</li>
       <li style="margin-bottom:10px;">	Hypomagnesemia (lower than normal magnesium in your blood; serum magnesium level lower than 1.8 mg/dL)</li>
       <li style="margin-bottom:10px;">	Hypocalcemia (lower than normal calcium in your blood; corrected serum calcium level lower than 2.12 mmol/L)</li>
       <li style="margin-bottom:10px;">Hypochloremia (lower than normal chloride in your blood; serum chloride level lower than 95 mEq/L)</li>
       <li style="margin-bottom:10px;">Metabolic alkalosis (a condition that occurs when your blood becomes overly alkaline; pH over 7.45)</li>
       <li style="margin-bottom:10px;">Hyperuricemia (abnormally high level of uric acid in the blood, affiliated with gout)</li>
       <li style="margin-bottom:10px;">Hyperglycemia (increased glucose in your bloodstream)</li>
       <li style="margin-bottom:10px;">Increased triglycerides</li>
       <li style="margin-bottom:10px;">Increased total <a href="https://www.marleydrug.com/blog/cholesterol-what-it-is-and-why-you-should-care">cholesterol</a></li>
       <li style="margin-bottom:10px;">Orthostatic hypotension (a condition in which your blood pressure quickly drops when you stand up from a sitting or lying position)</li>
       <li style="margin-bottom:10px;">Photosensitivity (extreme sensitivity to ultraviolet (UV) rays from the sun and other light sources)</li>
       <li style="margin-bottom:10px;">Ototoxicity (ear damage), including hearing loss, tinnitus, and vertigo </li>
</ul>

<h5 style="margin-bottom:10px; font-weight:600;">Drug interaction with loop diuretics:</h5>

<p>NSAIDs (Non-Steroidal Anti-Inflammatory Drugs)&mdash;should be avoided in individuals with heart failure. NSAIDs can increase sodium and water retention, which decreases the effect of the loop diuretics and can lead to renal impairment.</p>

<h2>Speak With Your Doctor</h2>

<p>Ask your healthcare provider which diuretic is the best fit for you and send your prescription to Marley Drug. Save up to 95% compared to your local pharmacy by using Marley Drug.</p>

Diuretics, known as water pills, are among the most frequently prescribed medications. These drugs are prescribed by doctors to treat a variety of ailments, including congestive heart failure and high blood pressure.

Diuretics (water pills)  are used to treat high blood pressure, heart failure, edema, liver failure, kidney disorders and glaucoma. Learn about different types, medications, side effects and interactions.

Diuretic - Types, Uses, and Side Effects

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What is Torsemide?

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Do you have worsening problems while taking a loop diuretic like torsemide?

Have medication questions?Talk with a pharmacist today.

What Our Customers Have to Say

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Kathy H

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Common Questions on Torsemide

Understanding Blood Pressure Readings

Why is it important to manage your blood pressure?

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