Questions? Call us at 800-810-7790
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Get Duloxetine (generic Cymbalta®) for $70/year


  • Wholesale pricing—so you pay less
  • Fill in longer supply—up to 12 months at a time
  • One price regardless of dose—no price fluctuations
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Fewer pharmacy visits. Fill in 30-, 90-, 180-, or 360-day supply at a time.

What is Duloxetine (Cymbalta)?

Duloxetine is a prescription based medication that helps to treat anxiety and depression. It belongs to a class of medications called selective serotonin reuptake inhibitors (SSRIs).

Duloxetine has been approved to treat the following mental health conditions:

Duloxetine has also been approved to treat other non-mental health conditions that are pain related. These include:

  • Diabetic peripheral neuropathic pain
  • Fibromyalgia
  • Chronic musculoskeletal pain


Common Questions about Duloxetine




Duloxetine is on Marley Drug’s Wholesale Price List

Our Wholesale Price List offers affordable pricing on many commonly prescribed generics. You can get Duloxetine (generic Cymbalta) either in a 12-month supply for $70 or a 6-month supply for $37.

Check our full list


How to Order Duloxetine

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Provide us your prescription details

Through our online portal you can provide us your medical history and prescription details. Questions? Call 800-810-7790.

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We'll verify your prescription

Our pharmacy team will verify your prescription details.

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Your medication will be shipped to your home

All medications are shipped by USPS First Class mail and will arrive in 2-3 business days.

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Pharmacists

Have medication questions?
Talk with a pharmacist today.

Call us for a free pharmacy consult.

800-810-7790

How does Duloxetine (Cymbalta) work?

Duloxetine is a selective serotonin reuptake inhibitor (SSRI). This type of medication works to increase the activity of serotonin, a chemical in our brain. Serotonin helps to increase happiness, stabilizes ones mood, and decreases obsessive and anxious thoughts.

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Common Questions about Duloxetine

What doses of Duloxetine are available?

At Marley Drug we have Duloxetine at 20mg, 30mg, 40mg and 60mg doses. All doses cost the same amount, so if you need to switch doses you should not see a change to your out of pocket costs.

Who should not take Duloxetine?

If you have liver disease severe kidney disease, or narrow-angle glaucoma (uncontrolled) you should not take Duloxetine. In addition, if you take certain medications like monoamine oxidase inhibitors or thioridazine you should not take duloxetine. Be sure to talk with your healthcare provider about all medications and medical conditions you have.

Can I take Duloxetine if I am pregnant?

It is generally recommended to avoid duloxetine if you are pregnant, planning to become pregnant, or are breastfeeding. Be sure to talk with your healthcare provider to weigh the pros and cons of staying on a medication that works for you versus the possible risks to the fetus.

What are the most common side effects of duloxetine?

The most common side effects experienced with duloxetine include:, nausea, dry mouth, fatigue, constipation, less appetite, and increased sweating. Importantly, some people may experience thoughts of hurting themselves or even suicide. If you experience any thoughts of hurting yourself or others at any time it is essential that you seek medical attention immediately. Be sure to tell your healthcare provider right away about how duloxetine, or any medication for that matter, affects you and the two of you can make an informed decision as to whether the medication is right for you.

How can Duloxetine work on anxiety and pain?

It is thought that duloxetine works in the same was for anxiety/depression as it does for pain, by increasing the amount of circulating serotonin and norepinephrine. This increase in thought to not only affect your mood, but also affect the nerve cells that help to decrease pain conduction.

How long will Duloxetine take to work?

Duloxetine, like nearly all SSRIs can take several weeks to get work. It takes roughly a week to have the medication at a steady concentration in your blood stream, and then another 1-3 weeks for your body to get used to the medication. During this period, side effects from the medication will also be at their worst, and should subside over time. If they do not, talk with your healthcare provider.

How long will it take to receive my Duloxetine order?

We have two options for your delivery service. USPS First Class Mail, which takes 2-3 business days and is free of charge. We also offer USPS Priority Delivery Express which takes 1-2 business days and will cost you $22.75.

How do I transfer my Duloxetine prescription to Marley Drug?

If you have an active prescription at another pharmacy, simply give us a call at 1-800-810-7790 and we’d be happy to request a transfer on your behalf.

Do you ship Duloxetine to all 50 states?

Marley Drug can dispense and ship medications to all 50 states as well as the District of Columbia and several U.S. territories (Guam, Puerto Rico, Virgin Islands).

Why is your price for Duloxetine so low?

We get that question a lot! We price ALL of our generic drugs based on what it costs us to acquire them. Most chain pharmacies price their generics based on what the brand version costs, even if it only costs them pennies to acquire the generic.

Do I require a prescription for Duloxetine?

Duloxetine is an FDA-approved medication. As a result, you require a prescription for this medication.

Articles on Mental Health and Duloxetine